DRUG RELATED PROBLEMS (DRPs) BERDASARKAN KATEGORI PCNE V6.2. PADA PASIEN HIPERTENSI GERIATRI DI INSTALASI RAWAT INAP RSUD TARAKAN JAKARTA

Stefanus Lukas, laura sonya

Abstract


High prevalence of using drug combination and pharmacokinetics and pharmacodynamics changes of age-related cause the geriatrics of hypertension patients who susceptible to drug related problems (DPSs). The purpose of this research to identification related problems on geriatrics of hypertension patients in RSUD Tarakan Jakarta which analyzed based PCNE V6.2. Data collected retrospectively using prescriptions, medical records and index records/nurse records. From 31 samples which got in inclusion criteria obtainable that primer hypertension was the most found (77,24%) and happened at 60 – 65 years old (51,61%). Long term care was ≤ 7 days (67,74%). The use of combination antihypertension drugs were 2 drugs (48,39%) and ACE Inhibitors was groups the most frequently used (32,05%). There were 124 causes from 83 DRPs incidences successfull identified. Percentage of therapeutic effectiveness issues (57,83%) and unwanted drug reactions (42,17%) with the biggest causes was because of inexactly combination of drug-drug or drug-meals include the incidence drugs interactions.

Tingginya prevalesi penggunaan kombinasi obat serta perubahan farmakokinetik dan farmakodinamik terkait usia menyebabkan pasien hipertensi usia lanjut rentan terhadap masalah terkait obat (DRPs). Tujuan dari penelitian ini adalah mengidentifikasi DRPs pada pasien rawat inap hipertensi geriatri di RSUD Tarakan Jakarta yang dianalisis berdasarkan PCNE V6.2. Pengambilan data dilakukan secara retrospektif menggunakan resep, rekam medis, kardeks/catatan perawat. Dari 31 sampel yang memenuhi kriteria inklusi diketahui bahwa hipertensi primer paling banyak ditemukan (77,24%) dan terjadi pada usia 60 – 65 tahun (51,61%). Lama masa perawatan ≤ 7 hari (67,74%). Penggunaan antihipertensi kombinasi 2 obat paling banyak digunakanan (48,39%) dan golongan yang paling sering digunakan adalah ACE Inhibitor (32,05%). Terdapat 124 penyebab dari 83 kejadian DRPs yang berhasil teridentifikasi. Persentase masalah efektivitas terapi (57,83%) dan reaksi obat yang tidak diinginkan (42,17%) dengan penyebab paling besar dikarenakan kombinasi obat-obat atau obat-makanan tidak tepat termasuk kejadian interaksi obat (39,52%).


Keywords


DRPs; Hipertensi; Antihipertensi; Geriatri; PCNE V6.2.; RSUD Tarakan Jakarta

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