FORMULASI DAN UJI STABILITAS SEDIAAN ANTISEPTIK FOOT SPRAY GEL MINYAK ATSIRI SERAI WANGI (Cymbopogon nardus (L.) Randle)

Kurnia Listiyanti, Diah Ramadhani

Abstract


The citronella plant is a plant that comes from the Poaceae family which has the main content of citronellal, citronellol and geraniol. Lemongrass essential oil is an essential oil that is often used as raw material for perfumes, antiseptics, cosmetics, medicines, food and beverage flavors and the aroma of kretek cigarettes. This research was conducted to determine the formulation and stability test antiseptic preparations lemongrass essential oil foot spray gel. This study carried out a spray gel formulation with various amounts of lemongrass essential oil made in four formulas, namely F1, F2, F3 and F4, the evaluation carried out in this study was organoleptic examination, homogeneity, pH, viscosity, dispersibility, adhesion spreadability, spray pattern & weight per spray, dry time, cycling test and hedonic. The antiseptic foot spray gel of lemongrass essential oil shows that the higher concentration of citronella essential oil contained in the formula, the more liquid preparation is, resulting in a decrease in the viscosity value and shows a little flow of sticky dispersion, whereas in the evaluation of the spreadability, weight per spray and Dry time showed an increase in each formula, meanwhile the stability evaluation using the cycling test method at F1, F2, F3 and F4 gave stable results except on organoleptic examinations in the aroma criteria that decreased the intensity of aromatic odors at F2, F3 and F4 at 6th cycle.

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References


Ladock, J. (2009, 2 September). How to Prevent Stinky Feet, Dikutip pada tanggal 17 September 2019 : http://www.healthguidance.org/entry/11520/1/How-toPrevent-Stinky-Feet.html.

Siskawati, Y., Bernadette, I., Menaldi, S.L., (2014). Bau Badan : Patogenesis dan Penatalaksanaan. 1, 32-41.

Sulaswatty, A, dkk., (2019). Quo Vadis Minyak Serai Wangi dan Produk Turunannya. Edisi 1. Jakarta : LIPI Press.

Parwata, I. M. O. A. dan Dewi, P. F. S. (2008). Isolasi dan uji aktivitas antibakteri minyak atsiri dari rimpang lengkuas (Alpinia galangal L). Jurnal Kimia. 2(2) : 100-104.

Poeloengan, M. (2009). Pengaruh Minyak Atsiri Serai (Andropogon citratus DC.) Terhadap Bakteri Yang Diisolasi Dari Sapi Mastitis Subklinis. Berita Biologi. 9(6) : 715-719.

Iswandana, R & Sihombing, L.K.M. (2017). Formulasi, Uji Stabilitas Fisik, dan Uji Aktivitas Secara In Vitro Sediaan Spray Antibau Kaki yang Mengandung Ekstrak Etanol Daun Sirih (Piper betle L.). Pharmaceutical Sciences & Research. 4(3) : 121 -131.

Manus, dkk. (2016). Formulasi Sediaan Gel Minyak Atsiri Daun Sereh (Cymbopogon citratus) Sebagai Antiseptik Tangan. PHARMACON Jurnal Ilmiah Farmasi. 5 (3) : 85-93.

Depkes, 1995. Farmakope Indonesia edisi keempat. Jakarta : Depkes RI.

Fitriansyah, S.N., dkk. (2016). Formulasi dan Evaluasi Spray Gel Fraksi Etil Asetat Pucuk Dau Teh Hijau (Camelian sinensis (L.) Kuntze). PHARMACY. 13(2) : 202 -216.

Kamishita, et al., (1992). Spray gel Base and Spray gel Preparation Using Thereof. United State Patent Application Publication. America.

Sukhibir, K. et al. (2013), Development of modified transdermal spray formulation of psoralen extract. Scholars Researce Library. Der Pharmacia Lettre, 5 (2) : 894.

Dewi, R.K. (2010). Optimasi Formulasi Mikroemulsi Sediaan Hormon Testosteron Undekanoat. Skripsi. Jakarta. Universitas Islam Negeri Syarif Hidayatullah.

Nisak, K., (2016). Uji Stabilitas Fisik dan Kimia Sediaan Gel Semprot Ekstrak Etanol Tumbuhan Paku (Nephrolepis falcata (Cav.) C. Chr.). Skripsi. Jakarta : UIN Syarif Hidayatullah Jakarta.

Rowe, R.C., Paul J.S., dan Marian. (2009). Handbook of Pharmaceutical 6th Edition. New York.

Barel, A., et al (2009). Skin pH and skin flora. In Handbook of Cosmetics Science and Technology. Third Edition. New York : Informa Healthcare USA.

Akhsani, L.W. (2017). Formulasi dan Uji Stabilitas Fisik-Kimia Sediaan Spray Gel Etil P-Metoksisinamat dari Rimpang Kencur (Kaempferia galangal Linn) dan Menthol. Skripsi. Jakarta : UIN Syarif Hidayatullah Jakarta.

Rajab, N. A. 2013. Preparation and Evaluation of Ketoprpfen as Dermal Spray Film. Kerbala Journal of Phaemaceutical Sciences Number 6.

Mappa, T., Edy, H.J., dan Kojong, N. (2013). Formulasi Gel Ekstrak Daun Sasaladahan (Peperomia Pellucida (L.) H.B.K.) dan Uji Efektivitasnya Terhadap Luka Bakar Pada Kelinci (Oryctolagus cuniculus). JIF UNSRAT. 2(02): 2303-2493.




DOI: https://doi.org/10.52447/inrpj.v6i1.4351

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