Telaah Tanaman Seledri (Apium graveolens L.) sebagai sumber bahan alam berpotensi tinggi dalam upaya promotif kesehatan

Taofik Rusdiana

Abstract


Indonesia sebagai negara dengan sumber kekayaan melimpah masih memiliki sejumlah keterbatasan dalam memanfaatkan dan mengolah sendiri sumber-sumber daya alamnya tersebut. Ribuan tanaman yang berpotensi memiliki khasiat dalam dunia kesehatan masih belum tergali. Pada tulisan ini ditinjau salah satu tanaman yang tumbuh dan hidup subur di negeri khatulistiwa ini yang ternyata memiliki segudang potensi di bidang pengobatan dan kesehatan, yaitu seledri (Apium graveolens L.). Kajian ini didasarkan kepada review article yang tersebar di database penelitian maupun dari hasil penelitian penulis sendiri. Seledri memiliki kandungan senyawa bioaktif seperti flavonoid (apiin dan apigenin), saponin, minyat atsiri (olein) dan oleoresin, ptalida (n-butil ptalida dan sedalonida) dan falcarinol dan falcarindiol. Zat-zat tersebut dilaporkan memiliki khasiat farmakologi sebagai diuretik, peluruh batu ginjal, antihipertensi, antihiperlipidemia, antioksidan, antiinflamasi dan antikanker.

Katakunci : Apium graveolens L., antikalkuli, antihipertensi, antihiperlipidemia, antiinflamasi, antioksidan


Full Text:

PDF

References


Daftar Pustaka

Ahmed B, A. T. (2002). Hepatoprotective activity of two plants belonging to the Apiaceae and the Euphorbiaceae family. J Ethnopharmacol, 79(3), 313-6.

Al-Asmari AK, A. M. (2017). An Updated Phytopharmacological Review on Medicinal Plant of Arab Region: Apium graveolens Linn. Pharmacogn Rev., 11(21), 13-18.

Alkofahi AS, A.-R. K. (2017). Report - Screening of the Anti-hyperglycemic activity of some medicinal plants of Jordan. Pak J Pharm Sci, 907-912.

Cheng MC, K. Y. (2010). Chemical synthesis of 9(Z)-octadecenamide and its hypolipidemic effect: a bioactive agent found in the essential oil of mountain celery seeds. J Agric Food Chem, 58(3), 1502-8.

Daraei, W. K. (2017). A Review of the Antioxidant Activity of Celery (Apium graveolens L). J Evid Based Complementary Altern Med, online first.

Hardani A, A. M. (2015). Effects of aqueous extract of celery (Apium graveolens L.) leaves on spermatogenesis in healthy male rats. Avicenna J Phytomed, 5(2), 113-9.

Hostetler G, R. K.-T. (2012). Flavone deglycosylation increases their anti-inflammatory activity and absorption. Mol Nutr Food Res, 56(4), 558-69.

Hu J, L. Z. (2015 ). Protective effect of apigenin on ischemia/reperfusion injury of the isolated rat heart. Cardiovasc Toxicol., 15(3), 241-9.

Iyer D, P. U. (2011). Effect of chloroform and aqueous basic fraction of ethanolic extract from Apium graveolens L. in experimentally-induced hyperlipidemia in rats. J Complement Integr Med, 8(1), 1-13.

Iyer D, P. U. (2011). Effect of chloroform and aqueous basic fraction of ethanolic extract from Apium graveolens L. in experimentally-induced hyperlipidemia in rats. J Complement Integr Med, 8(1), 1-13.

Iyer D, P. U. (2011). Effect of chloroform and aqueous basic fraction of ethanolic extract from Apium graveolens L. in experimentally-induced hyperlipidemia in rats. J Complement Integr Med, 8(1), 1-13.

Jorge VG, Á. J. (2013). Vasorelaxant activity of extracts obtained from Apium graveolens: possible source for vasorelaxant molecules isolation with potential antihypertensive effect. Asian Pac J Trop Biomed, 3(10), 776-9.

Ko FN, H. T. (1991). Vasodilatory action mechanisms of apigenin isolated from Apium graveolens in rat thoracic aorta. Biochim Biophys Acta, 1115(1), 69-74.

Kooti W, M. E.-L. (2014). The Effects of Hydroalcoholic Extract of Apium graveolens Leaf on the Number of Sexual Cells and Testicular Structure in Rat. Jundishapur J Nat Pharm Prod, 9(4), e17532.

Lans. (2006). Ethnomedicines used in Trinidad and Tobago for urinary problems and diabetes mellitus. J Ethnobiol Ethnomed, 2, 45.

Li MY, H. X. ( 2017). Advances in the research of celery, an important Apiaceae vegetable crop. Crit Rev Biotechnol., 1-12.

Li P, J. J. (2014). In vitro and in vivo antioxidant activities of a flavonoid isolated from celery (Apium graveolens L. var. dulce). Food Funct, 5(1), 50-6.

Liu T, L. F. (2012). Phytopathogenic fungal inhibitors from celery seeds. Nat Prod Commun, 7(7), 889-90.

Mencherini T, C. A. (2007). An extract of Apium graveolens var. dulce leaves: structure of the major constituent, apiin, and its anti-inflammatory properties. J Pharm Pharmacol, 59(6), 891-7.

Moghadam MH, I. M. (2013). Antihypertensive effect of celery seed on rat blood pressure in chronic administration. J Med Food, 16(6), 558-63.

Pałgan K1, G.-Ż. M. (2012 ). Celery--cause of severe anaphylactic shock. Postepy Hig Med Dosw , 66, 132-4.

Powanda MC, W. M. ( 2015). Celery Seed and Related Extracts with Antiarthritic, Antiulcer, and Antimicrobial Activities. Prog Drug Res, 70, 133-53.

Roman M., B. R. (2011). Nondestructive Raman analysis of polyacetylenes in apiaceae vegetables. J. Agric. Food Chem, 59: 7647–7653.

Rusdiana T, S. J. (2015). Anticalculi Activity Of Apium Graveolens L. Ethanol Extract Using Hydroxyproline Induced-Rat Method. International Seminar on Traditional and Alternative Medicine, 1.

Rusdiana T, S. J. (2015). Pengujian Efek Antikalkuli dari Herba Seledri (Apium graveolens L.). Indonesian Journal of Pharmaceutical Sciences and Technology, 2(2), 63-67.

Shivashri C, R. T. (2013). Hepatoprotective action of celery (Apium graveolens) leaves in acetaminophen-fed freshwater fish (Pangasius sutchi). Fish Physiol Biochem, 39(5), 1057-69.

Singh A, H. S. (1995). Hepatoprotective activity of Apium graveolens and Hygrophila auriculata against paracetamol and thioacetamide intoxication in rats. J Ethnopharmacol, 49(3), 119-26.

Sowbhagya. (2014). Chemistry, technology, and nutraceutical functions of celery (Apium graveolens L.): an overview. Crit Rev Food Sci Nutr, 54(3), 389-98.

Sultana S, A. S. (2005). Inhibitory effect of celery seeds extract on chemically induced hepatocarcinogenesis: modulation of cell proliferation, metabolism and altered hepatic foci development. Cancer Lett, 221(1), 11-20.

Tashakori-Sabzevar F, R. M. (2016). Protective and hypoglycemic effects of celery seed on streptozotocin-induced diabetic rats: experimental and histopathological evaluation. Acta Diabetol, 53(4), 609-19.

Tashakori-Sabzevar, R. M. (2016). Protective and hypoglycemic effects of celery seed on streptozotocin-induced diabetic rats: experimental and histopathological evaluation. Acta Diabetol, 53(4), 609-19.

Tsi D, D. N. (1995). Effects of aqueous celery (Apium graveolens) extract on lipid parameters of rats fed a high fat diet. Planta Med, 61(1), 18-21.

Tsi D, D. N. (1995). Effects of aqueous celery (Apium graveolens) extract on lipid parameters of rats fed a high fat diet. Planta Med, 61(1), 18-21.

Uddin Z, S. A. (2015). In vitro antimicrobial, antioxidant activity and phytochemical screening of Apium graveolens. Pak J Pharm Sci., 28(5), 1699-704.

Visutakul P, M. P. (1979). Effect of Koen--Chai or Chinese celery (Apium graveolens) on spermatogenesis. J Med Assoc Thai, 62(4), 164-73.

Yao Y, S. W. (2010). Phenolic composition and antioxidant activities of 11 celery cultivars. J Food Sci, 75(1), 9-13.




DOI: https://doi.org/10.52447/inspj.v3i1.874

Refbacks

  • There are currently no refbacks.


Copyright@ Pusat Penelitian Fakultas Farmasi

Universitas 17 Agustus 1945 Jakarta

Online ISSN : 2502-8421

 

Pengunjung